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Global Non-Alcoholic Steatohepatitis (NASH) Drugs Market: Industry Analysis & Outlook (2017-2026)
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Date: 09, October 2017 | Pages: 70
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Non-alcoholic steatohepatitis or NASH is a form of liver disease that causes inflammation and accumulation of fat tissues in the liver. It resembles alcoholic liver disease but occurs to those who drink too little or no alcohol. NASH shows no symptoms and is also known as a “Silent” liver disease. NASH can lead to cirrhosis, in which liver is permanently damaged and scarred and after a certain point, no treatment can cure it and thus lead to death.

 

There are two types of fatty liver disease: alcoholic fatty liver disease and non-alcoholic fatty liver disease (NAFLD). When inflammation is present with accumulation of fat in the liver then it is referred as NASH. Obesity and diabetes are most common cause of NASH disease. It is a challenge for the patient to recognize the accumulation of fat in the liver as patient experience no such symptoms until reach the advanced stage of the disease. The diagnosis of NASH includes blood tests, MRI, X-rays and liver biopsy.

 

Treatment of NASH includes managing and improving the condition of NASH from being worse and is recommended to bring changes in lifestyle and also use of off label drugs to control and manage indications related to NASH. Currently there is no approved drug in the market but is expected to enter the market in 2020. Currently, there are five potential Phase III drugs in the market including Elafibranor, Ocaliva (OCA), Cenicriviroc (CVC), Selonsertib and Aramchol.

 

The global NASH market is expected to show significant growth after the introduction of therapeutics drugs in 2020. Growth of market will mainly be driven by increasing patient base, rise in obese population, increasing type-2 diabetic population and increasing health expenditure. However, growth of market will also be hindered by absence of effective diagnostics, costly drugs, regulatory challenges and undefined pathogenesis.

 

The report “Global NASH Drugs Market: Industry Analysis & Outlook (2017-2026)” analyzes the development of this market, with focus on the US and Europe region. The major trends, growth drivers as well as issues being faced by the market are discussed in detail in this report. The four major players: Genfit SA, Intercept Pharmaceuticals, Inc., Allergan Plc. (Tobira) and Gilead Sciences are being profiled along with their key financials and strategies for growth. The report contains a comprehensive analysis of the global NASH market along with the study of the regional markets.
 

 

1. Market Overview

 

1.1 Nonalcoholic Steatohepatitis (NASH)
1.2 Causes & Symptoms
1.3 Diagnosis
1.4 Treatment

 

2. Global NASH Market

 

2.1 Global NASH Drugs Market Forecast by Value
2.2 Global NASH Drugs Market Forecast by Drug Class
2.3 Global NASH Off Label Drugs Market Forecast by Value

 

3. Global NASH Therapeutics Market

 

3.1 Global NASH Therapeutics Market Forecast by Value
3.2 Global NASH Therapeutics Market Forecast by Drug Type
3.3 Global NASH Therapeutics Market Forecast by Region
3.4 Global NASH Therapeutics Market by Type
3.4.1 Global Elafibranor Revenue Forecast by Value
3.4.2 Global Obeticholic Acid (OCA) Revenue Forecast by Value
3.4.3 Global Obeticholic Acid (OCA) Revenue Forecast by Region
3.4.4 Global Cenicriviroc (CVC) Revenue Forecast by Value
3.4.5 Global Cenicriviroc (CVC) Revenue Forecast by Region
3.4.6 Global Aramchol Revenue Forecast by Value

 

4. Regional NASH Market

 

4.1 The US
4.1.1 The US NASH Therapeutics Market Forecast by Value
4.2 The Europe
4.2.1 Europe NASH Therapeutics Market Forecast by Value
4.3 ROW
4.3.1 ROW NASH Therapeutics Market Forecast by Value

 

5. Market Dynamics

 

5.1 Growth Drivers
5.1.1 Rising Patient Base
5.1.2 Increasing Population with Type-2 Diabetes
5.1.3 Escalating Obese Population
5.1.4 Rising Healthcare Expenditure
5.1.5 Increasing GDP Per Capita
5.1.6 Vast Unmet Medical Need

 

5.2 Key Trends & Development
5.2.1 Strong Research & Development Efforts by Companies
5.2.2 Development of NASH Diagnosis Methods and Biomarkers

 

5.3 Challenges
5.3.1 Absence of Low-Priced and Effective Diagnostics
5.3.2 Regulatory Challenges and Undefined Pathogenesis
5.3.3 Costly NASH Therapeutics

 

6. Competitive Landscape

 

6.1 Revenue and Market Cap Comparison
6.2 Major Pipeline Products

 

7. Company Profiles

 

7.1 Genfit SA
7.1.1 Business Overview
7.1.2 Financial Overview
7.1.3 Business Strategies

 

7.2 Intercept Pharmaceuticals
7.2.1 Business Overview
7.2.2 Financial Overview
7.2.3 Business Strategies

 

7.3 Allergan (Tobira)
7.3.1 Business Overview
7.3.2 Financial Overview
7.3.3 Business Strategies

 

7.4 Gilead Sciences
7.4.1 Business Overview
7.4.2 Financial Overview
7.4.3 Business Strategies

 

List of Figures

 

Spectrum of Non-alcoholic Fatty Liver Disease (NAFLD)
Methods for NASH Diagnosis
Potential Phase III Drug Candidates
Global NASH Drugs Market Forecast by Value (2017-2026)
Global NASH Drugs Market Forecast by Drug Class (2017/2021/2026)
Global NASH Off Label Drugs Market Forecast by Value (2017-2026)
Global NASH Therapeutics Market Forecast by Value (2020-2026)
Global NASH Therapeutics Market Forecast by Drug Type (2021)
Global NASH Therapeutics Market Forecast by Drug Type (2026)
Global NASH Therapeutics Market Forecast by Region (2021)
Global NASH Therapeutics Market Forecast by Region (2026)
Global Elafibranor Revenue Forecast by Value (2020-2026)
Global Obeticholic Acid (OCA) Revenue Forecast by Value (2020-2026)
Global Obeticholic Acid (OCA) Revenue Forecast by Region (2026)
Global Cenicriviroc (CVC) Revenue Forecast by Value (2020-2026)
Global Cenicriviroc (CVC) Revenue Forecast by Region (2026)
Global Aramchol Revenue Forecast by Value (2022-2026)
The US NASH Therapeutics Market Forecast by Value (2020-2026)
Europe NASH Therapeutics Market Forecast by Value (2020-2026)
ROW NASH Therapeutics Market Forecast by Value (2020-2026)
The US NASH Market by Patient Population (2017-2026)
Global Type-2 Diabetes Population Forecast (2017-2026)
Global Obese Population (2012-2016)
Global Healthcare Expenditure Per Capita (2012-2016)
Global GDP Per Capita (2012-2016)
Genfit SA Revenue and Net Loss (2012-2016)
Genfit SA R&D Expenditure (2013-2016)
Intercept Pharmaceuticals Revenue and Net Income (2012-2016)
Intercept Pharmaceuticals R&D Expenditure (2013-2016)
Allergan (Tobira) Revenue by Segment (2016)
Allergan (Tobira) Revenue and Net Loss (2012-2016)
Allergan (Tobira) R&D Expenditure (2013-2016)
Gilead Sciences Revenue by Geographical Region (2016)
Gilead Sciences Revenue and Net Income (2012-2016)
Gilead Sciences R&D Expenditure (2013-2016)

 

List of Tables

 

Off Label Therapies for NASH (2016)
R&D Expenditure of Companies (2016)
Selected Diagnosis Methods in Development (2016)
NASH Key Players- Revenue and Market Cap Comparison (2016)
Key NASH Therapeutics Under Pipeline (2016)
Allergan (Tobira) Products Under Development for NASH (2016)

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