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Global Human Growth Hormone Market Report: 2015 Edition
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Date: 24, July 2015 | Pages: 53
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Pituitary - the master gland of human body is responsible for controlling crucial hormonal secretion, which, in turn, regulates other key aspects of the body such as temperature, growth, thyroid functioning, urination, and production of other hormones. It is a pea sized gland situated at the base of brain and is a major component of human body as it expedites the response towards the surrounding environment and settings.


Any deformity or damage to the pituitary gland can adversely impact the production and activity level of the above mentioned hormones, thereby affecting the body work process and stunting the outcomes especially in the case of growth hormone. Marred pituitary function leads to either over or under secretion of the somatropin that is the growth hormone. Its over secretion causes disfiguration in the body parts like hands, face, feet, etc. whereas, its deficiency impedes the growth of body parts/whole body, thus leading to disease states like dwarfism or gigantism.


It is observed that the growth hormone related problems usually affect children and teenagers, but it is seen to grip adults as well though to a lesser extent. The major factors which vitiate the pituitary operations thus impairing the GH role include kidney malfunction, tumors/cancer especially associated with brain. There are some other unknown causes as well which are termed as idiopathic. Earlier, to deal with these predicaments, growth hormone used to be extracted from the human cadavers but, as time passed and evolution of technology/tools/techniques/R&D took place, the extraction of GH also got altered and many novel innovations and discoveries were made in the respective field.


Nowadays, many leading companies are heavily involved in the R&D process for devising longer acting and sustained release versions of the somatropin which are produced using the recombinant technology. The competition prevalent in the respective industry is heating up day by day. The human growth hormone market is monopolized by a few players viz. Pfizer, NovoNordisk, Eli Lilly, Sandoz and Roche.


The global HGH report discusses the key ongoing trends like global agreement for Long-Acting Human Growth Hormone (HGH-CTP), increasing use of biosimilar version of drugs and continuous growth of recombinant growth hormones market. On the industry development front, the current inclination is towards developing better treatments for Alzheimer’s disease and advancements in needle free injections technology. Furthermore, the major factors driving the HGH market include rising cancer and CKD/ESRD cases and increasing healthcare expenditure on worldwide basis. In addition, a few factors posing challenges in front of the HGH industry are the problems in diagnosis of growth hormone deficiency, risks associated with use of recombinant growth hormone therapies and off-label HGH use which, to an extent, are hindering the growth and development of the same.


By combining SPSS Inc.’s data integration and analysis capabilities with our relevant findings, we have predicted the future growth of the industry. We employed various significant variables that have an impact on this industry and created regression models with SPSS Base to determine the future direction of the industry. Before deploying the regression model, the relationship between several independent or predictor variables and the dependent variable was analyzed using standard SPSS output, including charts, tables and tests. 

 

1. Human Growth Hormone


1.1 Physiological Effects of Growth Hormone
1.2 GH Secretion Control
1.3 GH Deficiency (GHD)
1.4 Therapeutic and Other Uses of GH/HGH
1.5 Recombinant Human Growth Hormone (rHGH)


2. Human Growth Hormone (HGH) Market Analysis


2.1 Global Market
-Market Value
-Market Volume
-Market Share
-Pediatric GHD Market


2.2 Regional Markets
-The US
-Europe
-Japan


2.3 VRS-317 Market Opportunity
2.4 TransCon-HGH Global Market Opportunity


3. Market Dynamics


3.1 Key Trends


3.1.1 Global Agreement for Long-Acting HGH-CTP
3.1.2 Increasing Use of Biosimilar Version of Drugs
3.1.3 Continuous Growth in rGH Market


3.2 Industry Developments


3.2.1 Developing Better Treatments for Alzheimer’s disease
3.2.2 Advancement in Needle Free Injection Technology


3.3 Growth Drivers


3.3.1 Increasing Cases of Chronic Kidney Disease (CKD)
3.3.2 Increasing Prevalence of Cancer
3.3.3 Rising Healthcare Expenditure
3.3.4 Increasing Global GDP


3.4 Challenges


3.4.1 Problems in Diagnosis of GHD
3.4.2 Risks Associated With Recombinant Human GH Therapy
3.4.3 Off-Label Uses of rHGH Therapy not Well Defined


4. Competitive Landscape


5. Company Profiles


5.1 Roche Holdings AG


5.1.1 Business Overview
5.1.2 Financial Overview
5.1.3 Business Strategies


5.2 Novo Nordisk


5.2.1 Business Overview
5.2.2 Financial Overview
5.1.3 Business Strategies


5.3 Pfizer, Inc.


5.3.1 Business Overview
5.3.2 Financial Overview
5.3.3 Business Strategies


5.4 Eli Lilly and Company


5.4.1 Business Overview
5.4.2 Financial Overview
5.4.3 Business Strategies


6. Market Outlook


6.1 Market Forecast
6.2 Forecast Methodology


6.2.1 Dependent and Independent Variables
6.2.2 Correlation Analysis
6.2.3 Regression Analysis  

List of Charts


GH’s Physiological Effect
GH Secretion Control
Global Human Growth Hormone Market Value (2010-2015)
Global Human Growth Hormone Market Volume (2010-2015)
Global HGH Market Share (2014)
Global HGH Sales by Growth Disorder Indication (2015E)
Worldwide Pediatric GHD Market Opportunity (2014-2020E)
The US Pediatric GHD Market (2014-2020E)
European Pediatric GHD Market (2014-2020E)
Japan’s Pediatric GHD Market (2014-2020E)
Global Pediatric GHD VRS-317 Market Opportunity (2018E-2024E)
Global TransCon HGH Market Opportunity (2019E-2024E)
Market Share of Omnitrope and Genotropin (Jan07-Oct12)
Quarterly Sales of rGH Products in USD (Jan10- Oct14)
People with Alzheimer’s disease in the US (2010-2050E)
Worldwide Patients with End Stage Renal Disease (2009-2014E)
Number of Cancer Cases Worldwide (2008-2014E)
Global Healthcare Spending Per Capita (2009-2014E)
Global Gross Domestic Product Growth (2009-2014E)
Net Income Comparison of Leading GH Producing Companies (2014)
R&D Budget of Top Growth Hormones Companies (2014)
Roche’s Revenues by Business Segments (2014)
Roche’s Sales and Net Income (2010-2014)
Novo Nordisk Revenue Share by Business Segments (2014)
Novo Nordisk’s Sales and Net Income (2010-2014)
Pfizer’s Revenue Share by Business Segments (2014)
Pfizer’s Sales & Net Income (2010-2014)
Eli Lilly’s Revenues by Segment (2014)
Eli Lilly’s Sales and Net Income (2010-2014)
Global HGH Market Forecast (2012-2018E)


List of Tables


VRS-317 US Market Opportunity (2014-2020E)
VRS-317 Europe Market Opportunity (2014-2020E)
VRS-317 Japan’s Market Opportunity (2014-2020E)
TransCon HGH US Market Opportunity (2014E-2020E)
TransCon HGH Europe Market Opportunity (2014E-2020E)
Needle Free Injectors by Technology
CKD Prevalence along with Disease Type (US)
Once Weekly HGH Competitive Landscape
Dependent & Independent Variables (2009-2014)
Correlation Matrix
Model Summary – Coefficient of Determination
Regression Coefficients Output 

1. Human Growth Hormone: An Overview
Pages : 7
USD 150

1.1 Physiological Effects of Growth Hormone
1.2 GH Secretion Control
1.3 GH Deficiency (GHD)
1.4 Therapeutic and Other Uses of GH/HGH
1.5 Recombinant Human Growth Hormone (rHGH)


Figure 1.1: GH’s Physiological Effect
Figure 1.2: GH Secretion Control
 

 
2. Human Growth Hormone (HGH) Market Analysis
Pages : 11
USD 300

2.1 Global Market
-Market Value
-Market Volume
-Market Share
-Pediatric GHD Market


2.2 Regional Markets
-The US
-Europe
-Japan


2.3 VRS-317 Market Opportunity
2.4 TransCon-HGH Global Market Opportunity


Figure 2.1: Global Human Growth Hormone Market Value (2010-2015)
Figure 2.2: Global Human Growth Hormone Market Volume (2010-2015)
Figure 2.3: Global HGH Market Share (2014)
Figure 2.4: Global HGH Sales by Growth Disorder Indication (2015E)
Figure 2.5: Worldwide Pediatric GHD Market Opportunity (2014-2020E)
Figure 2.6: The US Pediatric GHD Market (2014-2020E)
Figure 2.7: European Pediatric GHD Market (2014-2020E)
Figure 2.8: Japan’s Pediatric GHD Market (2014-2020E)
Figure 2.9: Global Pediatric GHD VRS-317 Market Opportunity (2018E-2024E)
Figure 2.10: Global TransCon HGH Market Opportunity (2019E-2024E)


Table 2.1: VRS-317 US Market Opportunity (2014-2020E)
Table 2.2: VRS-317 Europe Market Opportunity (2014-2020E)
Table 2.3: VRS-317 Japan’s Market Opportunity (2014-2020E)
Table 2.4: TransCon HGH US Market Opportunity (2014E-2020E)
Table 2.5: TransCon HGH Europe Market Opportunity (2014E-2020E) 

 
3. Market Dynamics
Pages : 9
USD 250

3.1 Key Trends


3.1.1 Global Agreement for Long-Acting HGH-CTP
3.1.2 Increasing Use of Biosimilar Version of Drugs
3.1.3 Continuous Growth in rGH Market


3.2 Industry Developments


3.2.1 Developing Better Treatments for Alzheimer’s disease
3.2.2 Advancement in Needle Free Injection Technology


3.3 Growth Drivers


3.3.1 Increasing Cases of Chronic Kidney Disease (CKD)
3.3.2 Increasing Prevalence of Cancer
3.3.3 Rising Healthcare Expenditure
3.3.4 Increasing Global GDP


3.4 Challenges


3.4.1 Problems in Diagnosis of GHD
3.4.2 Risks Associated With Recombinant Human GH Therapy
3.4.3 Off-Label Uses of rHGH Therapy not Well Defined


Figure 3.1: Market Share of Omnitrope and Genotropin (Jan07-Oct12)
Figure 3.2: Quarterly Sales of rGH Products in USD (Jan10- Oct14)
Figure 3.3: People with Alzheimer’s disease in the US (2010-2050E)
Figure 3.4: Worldwide Patients with End Stage Renal Disease (2009-2014E)
Figure 3.5: Number of Cancer Cases Worldwide (2008-2014E)
Figure 3.6: Global Healthcare Spending Per Capita (2009-2014E)
Figure 3.7: Global Gross Domestic Product Growth (2009-2014E)


Table 3.1: Needle Free Injectors by Technology
Table 3.2: CKD Prevalence along with Disease Type (The U.S.) 

 
4. Competitive Landscape
Pages : 3
USD 100

Figure 4.1: Net Income Comparison of Leading GH Producing Companies
Figure 4.2: R&D Budget of Top Growth Hormones Companies (2014)


Table 4.1: Once Weekly HGH Competitive Landscape 

 
5. Company Profiles
Pages : 11
USD 200

5.1 Roche Holdings AG


5.1.1 Business Overview
5.1.2 Financial Overview
5.1.3 Business Strategies


5.2 Novo Nordisk


5.2.1 Business Overview
5.2.2 Financial Overview
5.1.3 Business Strategies


5.3 Pfizer, Inc.


5.3.1 Business Overview
5.3.2 Financial Overview
5.3.3 Business Strategies


5.4 Eli Lilly and Company


5.4.1 Business Overview
5.4.2 Financial Overview
5.4.3 Business Strategies


Figure 5.1: Roche’s Revenues by Business Segments (2014)
Figure 5.2: Roche’s Sales and Net Income (2010-2014)
Figure 5.3: Novo Nordisk Revenue Share by Business Segments (2014)
Figure 5.4: Novo Nordisk’s Sales and Net Income (2010-2014)
Figure 5.5: Pfizer’s Revenue Share by Business Segments (2014)
Figure 5.6: Pfizer’s Sales & Net Income (2010-2014)
Figure 5.7: Eli Lilly’s Revenues by Segment (2014)
Figure 5.8: Eli Lilly’s Sales and Net Income (2010-2014) 

 
6. Market Outlook
Pages : 6
USD 150

6.1 Market Forecast
6.2 Forecast Methodology


6.2.1 Dependent and Independent Variables
6.2.2 Correlation Analysis
6.2.3 Regression Analysis


Figure 6.1: Global HGH Market Forecast (2012-2018E)


Table 6.1: Dependent & Independent Variables (2009-2014)
Table 6.2: Correlation Matrix
Table 6.3: Model Summary – Coefficient of Determination
Table 6.4: Regression Coefficients Output 

 
 
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